• Previous reports have implicated the guanylin GC C signallin

  2022-07-19

  

  Previous reports have implicated the guanylin/GC-C signalling system as being important in osmoregulation in fish, especially in euryhaline species such as the eel which migrate between freshwater (FW) and seawater (SW) environments at different stages of their life cycle (Comrie et al., 2001a, Comr

• br Acknowledgments This research was

  2022-07-19

  

  Acknowledgments This research was partially supported by the National Key Research and Development Program of China (2018YFD1000800); the National Natural Science Foundation of China (No. 31872943; No. 31501779 and No. 31372059>); 12th Five-Year State Science and Technology Support Program (2014B

• W123 The compounds described in this paper were prepared usi

  2022-07-19

  

  The compounds described in this paper were prepared using a modular approach that allowed diversification of R or R at the final step (). Route A involved amide coupling of -butyl 4-(methylamino)piperidine-1-carboxylate with phenyl acetic acids (step a) using 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-m

• Initial evidence that cell contact

  2022-07-19

  

  Initial evidence that cell-contact-mediated transmission of HIV-1 is relevant for the generation of latently infected cystic fibrosis chloride channel was suggested in the context of transmission from dendritic cells to resting CD4+ T cells (Evans et al., 2013, Kumar et al., 2015). As dendritic cel

• Initial evidence that cell contact

  2022-07-19

  

  Initial evidence that cell-contact-mediated transmission of HIV-1 is relevant for the generation of latently infected splenic volume calculator was suggested in the context of transmission from dendritic cells to resting CD4+ T cells (Evans et al., 2013, Kumar et al., 2015). As dendritic cells prob

• AG-1024 br Reaction mechanism The dissimilarity between

  2022-07-19

  

  Reaction mechanism The dissimilarity between monofunctional and bifunctional glycosylases is that the monofunctional glycosylases removes the substrate base, leaving an intact AP site while the bifunctional glycosylases have an additional lyase activity. This intrinsic lyase activity is present i

• To verify the feasibility of the proposed method EIS

  2022-07-19

  

  To verify the feasibility of the proposed method, EIS is firstly adopted to study the modification processes of the electrode. As shown in Fig. 1A, the nyquist plot of bare gold electrode exhibits a straight line, which indicates a fast charge transfer process (curve a). After modified with probe a,

• br Brief overview of the glutamate system

  2022-07-19

  

  Brief overview of the glutamate system and rationale for targeting the glycine site of NMDARs In the central nervous system (CNS), glutamate is the major excitatory neurotransmitter and works in concert with gamma-aminobutyric ion channels (GABA), the primary inhibitory neurotransmitter. Togethe

• Introduction The hypoglossal nucleus is

  2022-07-19

  

  Introduction The hypoglossal nucleus is the nucleus of the twelfth cranial nerve and is located on both sides of the mid line in the dorsal medulla oblongata and is situated between the proximal end of the medullary central canal and the beginning of the fourth ventricle (Tomasch and Etemadi, 1962)

• The neuronal glycine receptor HSOR allopregnanolone pathway

  2022-07-19

  

  The neuronal glycine receptor/3α-HSOR/allopregnanolone pathway may also be extended to the central nervous effects of gelsemine and koumine in brain. 3α-HSOR is expressed in certain brain regions in rats and humans, such as the limbic system including hypothalamus, hippocampus and amygdala, in addit

• Ajzenman et al reported improved stability and postural para

  2022-07-19

  

  Ajzenman et al reported improved stability and postural parameters in ASD children after EAT. Other authors presented similar findings,61, 62, 63, 64 although the studies were conducted among children with CP, and reported improved muscle symmetry,, stability of the head and the trunk, motor functio

• Although it is mainly a glial protein of total

  2022-07-19

  

  Although it is mainly a glial protein, 5–10% of total GLT-1 represents a neuronal form located at presynaptic terminals, but its physiological role remains elusive (for discussion, see (Rimmele and Rosenberg, 2016)). Nevertheless, this amount might be significant since GLT-1 has been estimated to be

• br Introduction Most organisms require glucose as a key meta

  2022-07-19

  

  Introduction Most organisms require glucose as a key metabolite, and it is critical that mammalian cells regulate glucose levels properly to maintain bioenergetic homeostasis. The major transporters responsible for the uptake of glucose from systemic circulation into cells are the GLUTs, members

• br Acknowledgments br Introduction Postmenopausal osteoporos

  2022-07-19

  

  Acknowledgments Introduction Postmenopausal osteoporosis, which is primarily caused by darolutamide deficiency, has been a worldwide health problem and threatens postmenopausal women of all races. An estimated 80% of osteoporosis patients in the United States are women, and approximately 30%

• br Methods br Results br Discussion

  2022-07-19

  

  Methods Results Discussion The measurement of intraocular pressure was made with a commercially available rebound tonometer, the Tonovet®. In our studies, Tonovet® underestimated the intraocular pressure in both animal models, being this effect more pronounced in the rat. To study the effe

16172 records 434/1079 page Previous Next First page 上5页 431432433434435 下5页 Last page