• Because R gene is positively regulated by T

  2023-01-04

  

  Because 5α-R2 gene is positively regulated by T and in the prostate gland (Torres et al., 2003), and our BPA-treated rats showed decreased circulating T and probably intraprostatic androgen levels, it might be responsible for the decrease of 5α-R2 expression. However, in a previous work using castra

• br Aromatase the key enzyme for estrogen

  2023-01-04

  

  Aromatase: the key enzyme for estrogen formation in adipose tissue Estrogens are synthesized from androgens by aromatase, a member of the cytochrome P450 superfamily, which is the rate-limiting enzyme in estrogen biosynthesis (Santen et al, 2009, Simpson et al, 1994). At the cellular level, aroma

• br Materials and methods br Results A first series

  2023-01-04

  

  Materials and methods Results A first series of experiments explored whether the Ampkα1 isoform is involved in the regulation of cardiac Pkcζ. To this end, HL-1 cardiomyocytes were transfected with a construct encoding constitutively active Prkaa1T183D (CAα1) or with the empty vector as contro

• br Antioxidant polymers conjugates Natural antioxidants are

  2023-01-04

  

  Antioxidant-polymers conjugates Natural antioxidants are usually used as a substitute for synthetics but some degradation phenomena could influence their applications. For example, ascorbic ipa chemical as a natural antioxidant undergoes yellowish coloration as a result of oxidation [29]. Sing a

• Numerous investigators have shown that RACK

  2023-01-04

  

  Numerous investigators have shown that RACK1 has several important, possibly related, roles in mRNA splicing and in translation. RACK1 interacts directly with specific components of the 40S ribosomal subunit (specifically, the 18S rRNA and ribosomal proteins rpS16e, rpS17e, and rpS3e [new names: uS9

• br Introduction Increased renin angiotensin system RAS activ

  2023-01-04

  

  Introduction Increased renin-angiotensin system (RAS) activity and inflammation in cardiovascular-related regions of the central nervous system contribute to the overactivity of neurohumoral systems that promote volume retention, cardiac remodeling and serious cardiac arrhythmias in systolic hear

• While high fat diet models of

  2023-01-04

  

  While high-fat diet models of insulin resistance are acceptable approaches for the study of pre-diabetes in humans, they are not suitable for modeling progression towards established type2 diabetes. The pattern of activation of the lipoxygenase pathway in pre-clinical models of type2 diabetes has no

• br Materials and Methods br Results In the Base

  2023-01-04

  

  Materials and Methods Results In the Base Analysis (53% of patients having access to the ALK test in both Current and Alternative Scenarios), a total of 16,583 patients were tested of whom 1,252 were assumed to be ALK-positive. A more extensive use of Ventana in the Alternative Scenario determ

• Increasing evidence indicates that ILCs participate in a

  2023-01-04

  

  Increasing evidence indicates that ILCs participate in a dialog with CD4+ T Magnolol [107–110]. This dialog is mediated, in part, through the expression of type II major histocompatibility complex (MHCII) molecules on ILC3s [107]. Depending on the expression of co-stimulatory molecules, MHCII:TCR i

• In a recent series of studies

  2023-01-04

  

  In a recent series of studies from our laboratory, to characterize the contractile systems within the rat Mdivi 1 synthesis wall, three conditions were identified that led to detrusor activity: spontaneous micro-contractions, electrical field stimulated (EFS) contractions and muscarinic agonist ind

• The rank order of agonist potency in turkey cardiac chambers

  2023-01-04

  

  The rank order of agonist potency in turkey cardiac chambers demonstrated the predominant presence of the β-adrenergic receptor subtype, in line with the receptor classification by . However, a previous radioligand binding study in the left ventricles of 7-week old turkeys reported the existence of

• iso 1 HT modulates cortical and hippocampal

  2023-01-04

  

  5-HT modulates cortical and hippocampal pyramidal cell function in a very complex manner, since most 5-HT receptor subtypes (excitatory as well as inhibitory) are expressed on pyramidal iso 1 as well as GABAergic interneurons that exert inhibitory control over pyramidal cells (Leiser et al., 2015,

• Autotaxin has been linked to chemoresistance through its

  2023-01-02

  

  Autotaxin has been linked to chemoresistance through its ability to inhibit apoptosis induced by paclitaxel in breast cancer glycyrrhizin receptor [15] and LPA can inhibit cell death induced by cisplatin [40]. Autotaxin was included in the present study because it was identified as being over-expre

• The use of FTAI can overcome the

  2023-01-02

  

  The use of FTAI can overcome the negative impact of low estrus detection efficiency, but implies effective synchrony of luteal function as well as synchronous growth and ovulation of a viable Risperidone follicle. Pregnancy rates obtained with FTAI may be comparable or better than those obtained aft

• br Conclusions The present protocol for localizing or spotti

  2023-01-02

  

  Conclusions The present protocol for localizing or “spotting” the site of action of an antioxidant in a micro-heterogeneous medium is based on the differences in its reactivity vis-à-vis the series of amphiphobic TEMPO derivatives 1a–f. Plots of the relative antioxidant effectiveness of a given A

16171 records 382/1079 page Previous Next First page 上5页 381382383384385 下5页 Last page